AGE Reader

The AGE Reader operates by detecting the autofluorescence of AGEs in the skin.

To perform a measurement, the patient simply places the inner forearm on the device, ensuring full contact with the measurement window.
The device emits ultraviolet light that induces tissue autofluorescence, directly correlated with AGE concentration in the skin.

The examination takes only 12 seconds, and results are displayed immediately, allowing for real-time assessment of cardiovascular risk alongside other clinical parameters.

The AGE Reader can be applied in multiple clinical and preventive contexts:

• Cardiovascular risk prevention:
  Identifies patients with high risk of cardiovascular complications, such as those with diabetes mellitus, renal failure, or acute coronary syndromes.

• Occupational and preventive health:
  Ideal for medical check-ups and corporate wellness programs, helping to identify individuals at risk for diabetes or metabolic syndrome.

• Anti-aging and dermatology:
  Useful in dermatology and cosmetic medicine to detect elevated AGE levels that contribute to skin aging, loss of elasticity, and oxidative damage.

Additionally, the AGE Reader serves as a motivational tool, helping patients understand and improve lifestyle habits while monitoring treatment effectiveness over time.

The AGE Reader is a certified medical device, combining innovation and practicality for clinical use.

Key advantages:

• Non-invasive:
  Performs the measurement directly on the skin without the need for blood samples or biopsies.
  The use of UV light is completely safe and causes no tissue damage.

• Fast results:
  The measurement takes only 12 seconds, with immediate results, enabling real-time clinical decisions.

• Scientifically validated:
  Supported by over 300 scientific publications, confirming its reliability in cardiovascular risk assessment.

• Long-term predictive value:
  AGEs are cumulative biomarkers of oxidative stress and chronic inflammation.
  The AGE Reader provides a biological damage assessment independent of short-term fluctuations in blood glucose or other lab parameters.

• Ease of use:
  Simple interface requiring minimal training — ideal for large-scale screening programs.

• Versatility:
  Applicable in multiple fields, including internal medicine, diabetology, nephrology, cardiology, occupational medicine, and geriatrics, as well as in preventive and anti-aging programs.

• Ongoing monitoring:
  Allows evaluation of the effectiveness of lifestyle changes or pharmacological treatments over time.

The AGE Reader has been validated against the gold standard method for AGE quantification: skin biopsy.

Since 2006, it has been used in both clinical practice and research, validated in over 300 clinical studies demonstrating that skin autofluorescence is an independent predictor of micro- and macrovascular complications, particularly in type 2 diabetes and renal disease patients.

The device has been employed in multicenter international studies and validated across large patient populations.

AGE levels correlate directly with vascular damage in diabetic patients and help identify individuals at risk of cardiovascular complications.

The AGE Reader App is specialized software developed to generate comprehensive cardiovascular risk reports based on AGE measurements, integrated with additional risk factors.

Measurements can be exported directly from the device to a computer via Bluetooth connection.

All examinations are recorded and easily accessible, allowing for long-term patient monitoring and treatment management.

Reports can be printed, saved, or exported, facilitating data sharing with other healthcare professionals or with the patient.

Each report features clear graphical representations that enhance patient understanding of their cardiovascular risk and promote greater treatment adherence.

The app is available for Windows and Mac operating systems.